Dry Powder Cefoperazone Sulbactam Injection , Cephalosporin Antibiotics

Dry Powder Cefoperazone Sulbactam Injection , Cephalosporin Antibiotics

Product : Cefoperazone Sodium and Sulbactam Sodium for Injection 2:1; 1:1

Specification : 0.75g; 1.5g; 2.0g; 2.25g; 3.0g

Standard : BP, USP

Description:

Cefoperazone is a semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It has been proposed especially against Pseudomonas infections.

Sulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys the antibiotics.

Indication

For the treatment of bacterial infections caused by susceptible microorganisms.

Pharmacodynamics

Cefoperazone is a third generation cephalosporin antibiotic. Cefoperazone exerts its bactericidal effect by inhibiting the bacterial cell wall synthesis

Mechanism of action

Like all beta-lactam antibiotics, cefoperazone binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.