|Place of Origin:||China|
|Model Number:||3.5%, 250ml, 500ml|
|Minimum Order Quantity:||40, 000 bottles|
|Packaging Details:||40 / 20 bottles per carton|
|Payment Terms:||L/C, T/T|
|Supply Ability:||200, 000 bottles per day|
|Product:||Polygeline Injection||Specification:||3.5%, 250ml, 500ml|
|Standard:||USP, BP||Packing:||40 / 20 Bottles Per Carton|
Hypovolaemic Shock Polygeline Injection 250ml 500ml Large Volume
Product : Polygeline Injection
Specification : 3.5%, 250ml, 500ml
Standard : USP, BP
Packing : 40 / 20 bottles per carton
Polygeline is a plasma substitute for volume replacement used to correct or avert circulatory insufficiency due to plasma/blood volume deficiency, either absolute (e.g. resulting from bleeding) or relative (e.g. resulting from a shift in plasma volume between the circulatory compartments).
Polygeline is applied in the following areas :
Loss of blood and plasma (e.g. due to trauma, burns, autologous blood or plasma donation before an operation)
For filling the heart-lung machine. In addition Polygeline can be used as a carrier solution for various drugs.
Known hypersensitivity to constituents of the preparation. Existing severe allergic reactions. In the following cases, Polygeline is indicated to a restricted extent only. If the physician considers the infusion necessary, it should be given taking special precautions: All conditions in which an increase in intravascular (blood vessel) volume and its consequences (e.g. increased stroke volume, elevated blood pressure), or an increase in interstitial fluid volume or haemodilution could represent a particular risk for the patient.
Examples of such conditions are: congestive heart failure, hypertension, oesophageal varices, pulmonary oedema, haemorrhagic diathesis, renal and postrenal anuria. In all patients at an increased risk of histamine release (e.g. persons with allergic/allergoid reactions and patients with a history of histamine response).
In the latter cases Polygeline may be given only after taking appropriate prophylactic steps. Use of the preparation in pregnant women and nursing mothers is not contraindicated.
Measures of Precaution For Administration
For physiological reasons Polygeline should not be infused in the cold state, like all infusion solutions. Infuse clear solutions only. Reactions caused by histamine release can be avoided by the prophylactic use of H1 and H2 receptor antagonists (e.g. Dimetinden 0.1mg/kg of body weight I.V. and Cimetidin 5mg/kg of body weight iv.).
For technical reasons there is a residual air volume in the container. Thus, pressure infusions with the plastic infusion bottle must be carried out under controlled conditions only, as the risk of an air embolism cannot be excluded. Expel air prior to infusion under pressure.
Interactions with Other Agents
In the case of patients receiving cardiac glycosides, the synergistic effect of the calcium in Polygeline should be taken into account.