Diclofenac Suppository Medication / Anti Inflammatory Suppository 75 mg

Diclofenac Suppository Medication / Anti Inflammatory Suppository 75 mg

Product : Diclofenac Suppository

Specification : 75mg

Standard : In - house

Packing : 6's/blister, 2 blisters per box

Description :

Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.

Indication :

For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.

Pharmacodynamics :

Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis

Mechanism of action :

The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.