Ipratropium Bromide Aerosol Medication , Pressurized Metered Dose Inhaler

Ipratropium Bromide Aerosol Medication , Pressurized Metered Dose Inhaler

Ipratropium Bromide Aerosol Metered 20mcg/Dose, 200doses Aerosol Medication

Product : Ipratropium Bromide Aerosol Metered

Specification : 20mcg/Dose, 200doses

Standard : BP, USP

Packing : one bottle/box

Description :

Ipratropium Bromide Aerosol HFA is an inhalation aerosol supplied in a pressurized stainless steel canister as a metered-dose inhaler with a mouthpiece and a protective cap. After priming, each actuation of the inhaler delivers 20mcg actuation of ipratropium bromide (as the monohydrate).

BP standard.

Indication :

The product is an anticholinergic indicated for the maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

Pharmacodynamics

Ipratropium bromide, a synthetic ammonium compound structurally similar to atropine, is used as a bronchodilator in the management of cholinergic-mediated bronchospasm associated with chronic obstructive pulmonary disease and in the treatment of rhinorrhea associated with the common cold or with allergic or nonallergic seasonal rhinitis.

Mechanism of action

Ipratropium bromide is an anticholinergic agent. It blocks muscarinic cholinergic receptors, without specificity for subtypes, resulting in a decrease in the formation of cyclic guanosine monophosphate (cGMP). Most likely due to actions of cGMP on intracellular calcium, this results in decreased contractility of smooth muscle.