|Place of Origin:||China|
|Model Number:||0.5g, 1.0g|
|Minimum Order Quantity:||100, 000 vials|
|Payment Terms:||L/C, T/T|
|Supply Ability:||500, 000 vials per day|
|Product:||Cefazolin Sodium For Injection||Product:||Cefazolin Sodium For Injection|
|Specification:||0.5g, 1.0g||Specification:||0.5g, 1.0g|
|Standard:||BP, USP||Standard:||BP, USP|
Antibiotic Dry Powder Injection / Cefazolin Sodium Injection Antibiotic Action
Product : Cefazolin Sodium for Injection
Specification : 0.5g, 1.0g
Standard : BP, USP
Packing : 50vials/box
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis; if required metronidazole may be added to cover B. fragilis.
Cefazolin (also known as cefazoline or cephazolin) is a semi-synthetic first generation cephalosporin for parenteral administration. Cefazolin has broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Mechanism of action :
In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.