|Place of Origin:||China|
|Minimum Order Quantity:||10000 vials|
|Packaging Details:||10 vials/box|
|Payment Terms:||L/C, T/T|
|Supply Ability:||50, 000 vials per day|
|Product:||Recombinant Human Erythropoietin Injection RHuEPO||Specification:||2000//3000/4000/10000IU|
|Standard:||In - House||Packing:||10vials/box|
Recombinant Human Erythropoietin Injection rHuEPO HIV Treatment
Product : Recombinant Human Erythropoietin Injection rHuEPO
Specification : 2000//3000/4000/10000IU
Standard : In - house
Packing : 10vials/box
Erythropoietin (as Epoetin alfa) is a 165-amino acid erythropoiesis-stimulating glycoprotein manufactured by recombinant DNA technology. It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. The product contains the identical amino acid sequence of isolated natural erythropoietin.
For treatment of anemia (from renal transplants or certain HIV treatment)
Used in the treatment of anemia. Involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
Mechanism of action
Binding of erythropoietin to the erythropoietin receptor leads to receptor dimerization, which facilitates activation of JAK-STAT signaling pathways within the cytosol. Activated STAT (signal transducers and activators of transcription) proteins are then translocated to the nucleus where they serve as transcription factors which regulate the activation of specific genes involved in cell division or differentiation.