Ibuprofen for Oral Suspension 100mg/5ml; 100ml Oral Medications Ibuprofen Dry Syrup

Ibuprofen for Oral Suspension 100mg/5ml; 100ml Oral Medications Ibuprofen Dry Syrup

Product : Ibuprofen for Oral Suspension

Specification : 100mg/5ml; 100ml

Standard : BP, USP

Packing : one bottle/box

Description :

Ibuprofen 100 mg/5 ml Oral Suspension contains Ibuprofen as the active ingredient. This belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Ibuprofen Paediatric Oral Suspension is given to children as a painkiller for relief of mild to moderate muscular pain, headache, earache, sore throat, dental pain and backache.

This medicine can also be used in minor injuries such as sprains and strains. It also reduces the temperature in fever (e.g. colds, influenza and post-immunisation fever).

INDICATIONS AND USAGE

temporarily:

relieves minor aches and pains due to the common cold, flu, sore throat, headache and toothache

reduces fever

Pharmacodynamics

Ibuprofen is a nonsteroidal anti-inflammatory agent (NSAIA) or nonsteroidal anti-inflammatory drug (NSAID), with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, which are thought to act through inhibition of prostaglandin synthesis.

Mechanism of action

The exact mechanism of action of ibuprofen is unknown. Ibuprofen is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 (COX-2) which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI ulceration. Ibuprofen is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomer in vivo. The S-enantiomer is believed to be the more pharmacologically active enantiomer.