Tacrolimus Capsules 0.5mg, 1mg, 5mg Oral Medications

Tacrolimus Capsules 0.5mg, 1mg, 5mg Oral Medications

Product : Tacrolimus Capsules

Specification : 0.5mg, 1mg, 5mg

Standard : BP, USP

Packing : 10’s/blister

Description:

Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis. Tacrolimus Capsule is for oral administration as capsules containing the equivalent of 0.5 mg, 1 mg or 5 mg of anhydrous tacrolimus.

Indications and Usage :

1. Prophylaxis of Organ Rejection in Kidney Transplant

Tacrolimus capsules is indicated for the prophylaxis of organ rejection in patients receiving allogeneic kidney transplants. It is recommended that Tacrolimus capsules be used concomitantly with azathioprine or mycophenolate mofetil (MMF) and adrenal corticosteroids. Therapeutic drug monitoring is recommended for all patients receiving Tacrolimus capsules.

2. Prophylaxis of Organ Rejection in Liver Transplant

Tacrolimus capsules is indicated for the prophylaxis of organ rejection in patients receiving allogeneic liver transplants. It is recommended that Tacrolimus capsules be used concomitantly with adrenal corticosteroids. Therapeutic drug monitoring is recommended for all patients receiving Tacrolimus capsules.

3. Prophylaxis of Organ Rejection in Heart Transplant

Tacrolimus capsules is indicated for the prophylaxis of organ rejection in patients receiving allogeneic heart transplants. It is recommended that tacrolimus capsules be used concomitantly with azathioprine or mycophenolate mofetil (MMF) and adrenal corticosteroids. Therapeutic drug monitoring is recommended for all patients receiving tacrolimus capsules.

4. Limitations of Use

Tacrolimus capsules should not be used simultaneously with cyclosporine.

Tacrolimus injection should be reserved for patients unable to take tacrolimus capsules orally.

Use with sirolimus is not recommended in liver and heart transplant. The safety and efficacy of Tacrolimus capsules with sirolimus has not been established in kidney transplant.