801-2, Jindong Mansion, No. 536 Xueshi Road, Yinzhou, Ningbo 315100, P.R.China | info@newlystar-medtech.com |
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Place of Origin: | China |
Brand Name: | Newlystar |
Certification: | GMP |
Model Number: | 10mg |
Minimum Order Quantity: | 500, 000 tablets |
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Price: | Negotiation |
Packaging Details: | 10’s/blister |
Delivery Time: | 45days |
Payment Terms: | L/C, T/T |
Supply Ability: | One million pills per day |
Product: | Montelukast Sodium Tablets | Specification: | 10mg |
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Standard: | BP, USP | Packing: | 10’s/blister |
High Light: | oral medicine,oral preparation |
Montelukast Sodium Tablets 10mg Oral Medications
Product : Montelukast Sodium Tablets
Specification : 10mg
Standard : BP, USP
Packing : 10’s/blister
Description :
Montelukast sodium, the active ingredient in montelukast sodium tablets, is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor.Montelukast sodium is a hygroscopic, optically active, white to off-white powder. Montelukast sodium is freely soluble in ethanol, methanol, and water and practically insoluble in acetonitrile.
Each 10-mg film-coated montelukast sodium tablet contains 10.4 mg montelukast sodium, which is equivalent to 10 mg of montelukast.
Indications and Usage :
1. Asthma
Montelukast sodium is indicated for the prophylaxis and chronic treatment of asthma in adults and pediatric patients 12 months of age and older.
2. Exercise-Induced Bronchoconstriction
Montelukast sodium is indicated for prevention of exercise-induced bronchoconstriction (EIB) in patients 15 years of age and older.
Pediatric use information for patients ages 6 to 14 years of age for acute prevention of exercise-induced bronchoconstriction (EIB) is approved for Merck Sharp & Dohme Corp's montelukast tablet products. However, due to Merck Sharp & Dohme Corp's marketing exclusivity rights, this drug product is not labeled with that pediatric information.
3. Allergic Rhinitis
Montelukast sodium is indicated for the relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older and perennial allergic rhinitis in patients 6 months of age and older.
Pharmacodynamics
Montelukast, like zafirlukast, is a leukotriene receptor antagonist used as an alternative to anti-inflammatory medications in the management and chronic treatment of asthma and exercise-induced bronchospasm (EIB). Unlike zafirlukast, montelukast does not inhibit CYP2C9 or CYP3A4 and is, therefore, not expected to affect the hepatic clearance of drugs metabolized by these enzymes.
Mechanism of action
Montelukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Montelukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Contact Person: Mr. Luke Liu
Tel: 86--57487019333
Fax: 86-574-8701-9298
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