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In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism

In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism

In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism

Product Details:

Place of Origin: China
Brand Name: Newlystar
Certification: GMP
Model Number: 50mcg, 100mcg

Payment & Shipping Terms:

Minimum Order Quantity: 500, 000 tablets
Price: Negotiation
Packaging Details: 10’s/blister
Delivery Time: 45days
Payment Terms: L/C, T/T
Supply Ability: one million pills per day
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Detailed Product Description
Product: Levothyroxine Tablets Specification: 50mcg, 100mcg
Standard: In - House Packing: 10’s/blister

In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism

 

 

Product : Levothyroxine Tablets

Specification : 50mcg, 100mcg

Standard : In - house

Packing : 10’s/blister

 

Description :

Levothyroxine is a major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism.

 

Indication

For use alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.

 

Pharmacodynamics

Levothyroxine (T4) is a synthetically prepared levo isomer of thyroxine, the major hormone secreted from the thyroid gland. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine (T3) which exerts a broad spectrum of stimulatory effects on cell metabolism. Thyroid hormone increases the metabolic rate of cells of all tissues in the body. In the fetus and newborn, thyroid hormone is important for the growth and development of all tissues including bones and the brain. In adults, thyroid hormone helps to maintain brain function, food metabolism, and body temperature, among other effects. The symptoms of thyroid deficiency relieved by levothyroxine include slow speech, lack of energy, weight gain, hair loss, dry thick skin and unusual sensitivity to cold.

 

Mechanism of action

Levothyroxine acts like the endogenous thyroid hormone thyroxine (T4, a tetra-iodinated tyrosine derivative). In the liver and kidney, T4 is converted to T3, the active metabolite. In order to increase solubility, the thyroid hormones attach to thyroid hormone binding proteins, thyroxin-binding globulin, and thyroxin-binding prealbumin (transthyretin). Transport and binding to thyroid hormone receptors in the cytoplasm and nucleus then takes place. Thus by acting as a replacement for natural thyroxine, symptoms of thyroxine deficiency are relieved.

Contact Details
Newlystar (Ningbo) Medtech Co.,Ltd.

Contact Person: Luke Liu

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