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Finasteride Tablets Oral Medications , Film Coated Tablets for Hair Loss

Finasteride Tablets Oral Medications , Film Coated Tablets for Hair Loss

Finasteride Tablets Oral Medications , Film Coated Tablets for Hair Loss

Product Details:

Place of Origin: China
Brand Name: Newlystar
Certification: GMP
Model Number: Film-coated Tablets, 1mg, 5mg, 10mg

Payment & Shipping Terms:

Minimum Order Quantity: 500, 000 tablets
Price: Negotiation
Packaging Details: 12’s/blister
Delivery Time: 45days
Payment Terms: L/C, T/T
Supply Ability: one million pills per day
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Detailed Product Description
Product: Finasteride Tablets Specification: Film-coated Tablets, 1mg, 5mg, 10mg
Standard: BP, USP Packing: 12’s/blister

Finasteride Tablets Oral Medications , Film Coated Tablets for Hair Loss

 

 

Product : Finasteride Tablets

Specification : Film-coated Tablets, 1mg, 5mg, 10mg

Standard : BP, USP

Packing : 12’s/blister

 

Description :

Finasteride is an orally active testosterone 5-alpha-reductase inhibitor. It is used as a surgical alternative for treatment of benign prostatic hyperplasia.

 

Indication

For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostate. Also used for the stimulation of regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness).

 

Pharmacodynamics

Finasteride is a synthetic 4-azasteroid compound. This drug is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). Two distinct isozymes are found in mice, rats, monkeys, and humans: Type I and II. Each of these isozymes is differentially expressed in tissues and developmental stages. In humans, Type I 5a-reductase is predominant in the sebaceous glands of most regions of skin, including scalp, and liver. Type I 5a-reductase is responsible for approximately one-third of circulating DHT. The Type II 5a-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles as well as liver, and is responsible for two-thirds of circulating DHT. Although finasteride is 100-fold more selective for type II 5a-reductase than for the type I isoenzyme, chronic treatment with this drug may have some effect on type I 5a-reductase.

 

Mechanism of action

The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-reductase through the formation of a stable complex with the enzyme. Inhibition of Type II 5a-reductase blocks the peripheral conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT concentrations, minimal to moderate increase in serum testosterone concentrations, and substantial increases in prostatic testosterone concetrations. As DHT appears to be the principal androgen responsible for stimulation of prostatic growth, a decrease in DHT concentrations will result in a decrease in prostatic volume (approximately 20-30% after 6-24 months of continued therapy). In men with androgenic alopecia, the mechanism of action has not been fully determined, but finasteride has shown to decrease scalp DHT concentration to the levels found in hairy scalp, reduce serum DHT, increase hair regrowth, and slow hair loss.

Contact Details
Newlystar (Ningbo) Medtech Co.,Ltd.

Contact Person: Luke Liu

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