|Place of Origin:||China|
|Minimum Order Quantity:||300, 000 tablets|
|Payment Terms:||L/C, T/T|
|Supply Ability:||one million pills per day|
|Product:||Cyproterone Acetate Tablets||Specification:||50mg|
|Standard:||In - House||Packing:||10’s/blister|
Oral Medicine Cyproterone Acetate Tablets 50mg Luteinizing Hormone Supplement
Product : Cyproterone Acetate Tablets
Specification : 50mg
Standard : In - house
Packing : 10’s/blister
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Indications in the man
1. Antiandrogen treatment in inoperable carcinoma of the prostate
2. Reduction of drive in sexual deviations
Indications in the woman
Severe signs of androgenization, e.g. very severe hirsutism in the female, severe androgenetic alopecia, often attended by severe forms of acne and/or seborrhoea.
Cyproterone is an antiandrogen. It suppresses the actions of testosterone (and its metabolite dihydrotestosterone) on tissues. It acts by blocking androgen receptors which prevents androgens from binding to them and suppresses luteinizing hormone (which in turn reduces testosterone levels).
Mechanism of action
The direct antiandrogenic effect of cyproterone is blockage of the binding of dihydrotestosterone to the specific receptors in the prostatic carcinoma cell. In addition, cyproterone exerts a negative feed-back on the hypothalamo-pituitary axis, by inhibiting the secretion of luteinizing hormone resulting in diminished production of testicular testosterone.